ODCs

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3 associated genes
4 signs/symptoms

PROTEIN INTERACTIONS: 1

1 OMIM reference -
1 associated gene
4 signs/symptoms

Well-differentiated liposarcoma

Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	CDK4	(0.72)	IRF8

Citations in the biomedical literature:

Well-differentiated liposarcoma		Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency
	Synonym(s): - ALT - Atypical lipoma - Atypical lipomatous tumor - WDLS		Synonym(s): - MSMD due to partial IRF8 deficiency - MSMD due to partial interferon regulatory factor 8 deficiency - Mendelian susceptibility to mycobacterial diseases due to partial interferon regulatory factor 8 deficiency

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare immune disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: normal Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Well-differentiated liposarcoma		Mendelian susceptibility to mycobacterial diseases due to partial IRF8 deficiency
	Very frequent - Soft tissue sarcoma / cancer / tumor / liposarcoma / myosarcoma - Subcutaneous nodules / lipomas / tumefaction / swelling Occasional - Functional anomalies of the kidney and the urinary tract - Intestinal transit disorder		Very frequent - Autosomal dominant inheritance - Fever / chilling - Immunodeficiency / increased susceptibility to infections / recurrent infections - Lymphadenopathy / polyadenopathies